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Abstract
Review ini bertujuan untuk mengkaji pengaruh pemberian probiotik terhadap respon biokimia darah ayam broiler berdasarkan hasil-hasil penelitian terkini dari jurnal nasional terakreditasi SINTA dan jurnal internasional terindeks Scopus. Metode yang digunakan adalah studi literatur terhadap 20 artikel ilmiah yang diterbitkan antara tahun 2016 hingga 2024. Hasil kajian menunjukkan bahwa pemberian probiotik seperti Lactobacillus sp., Bacillus subtilis, dan Saccharomyces cerevisiae mampu memperbaiki profil hematologi dan biokimia darah ayam broiler. Probiotik terbukti menurunkan kadar kolesterol, trigliserida, dan LDL darah, meningkatkan jumlah eritrosit, hemoglobin, dan hematokrit, serta memperbaiki profil leukosit sebagai indikator sistem kekebalan tubuh. Mekanisme kerja probiotik meliputi modulasi mikrobiota usus, peningkatan integritas mukosa usus, serta stimulasi sistem imun. Secara keseluruhan, probiotik berpotensi besar menjadi alternatif alami pengganti antibiotik dalam meningkatkan kesehatan dan performa ayam broiler secara berkelanjutan.
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